Introduction: Physical disability is an inability to perform all or part of personal or social life activities because of congenital problems or defects in physical and mental potency. The impact of disability on social / psychological position of individuals is undeniable. The aim of this study was to evaluate the effect of life skills training on the adaptation and resilience in adolescents with physical disabilities.

Methods: Method of this study was quasi-experimental with pre-test and post-test with the control and experimental groups. The population of this study was all adolescents with physical disabilities in Shirvan city in 2015. The statistical sample was included 30 adolescents with disabilities who were selected through available sampling method, and then randomly assigned 15 adolescents in the experimental group and 15 adolescents in the control group. First conducted pretest on both of groups and then the experimental group received life skills training in 9 sessions (90 minutes). After training, post-test was conducted on both of groups.

Results: The results showed that life skills training had significant effect on adaptation and resilience in adolescents with physical disabilities (P < 0.05).

Conclusions: Learning life skills can be crucial for the success and adjustment in life. Children with disabilities may not be able to learn many of these skills without training. So we have to teach directly them these skills so that they can overcome life challenges and achieve more success.