Introduction: One of the most common and most debilitating problems of youth and adolescents is depression and according to extent of the outbreak, it is called as mental cold. This study aimed to investigate the prevalence of depression and associated factors in adolescents of masjed soleyman in 2014.

Methods: In this descriptive-cross sectional survey, 338 people as stratified sampling from first high school boys and girls students of Masjed-Soleyman were enrolled. For gathering data depression Janbozorgi Questionnaire for Children and Adolescents (CADs) and demographic questionnaire were used.

Results: In this study, %86.7 of the students had some degree of depression. The mean score of depression in this study was obtained 10.17 ± 7.21, which indicates moderate depression. In general, there were a significant correlation between the average depression score and gender, father's occupation, type of school, leisure and non-school classes, work in leisure time, number of family members and close friends (P<0/05). But the relationship between the mother's job, death of a family member, smoking experienced and the mean depression score were not statistically significant (P> 0/05).

Conclusions: According to the results, this adolescents, especially girls, need to strategies and psychosocial support such as registering for classes leisure, prevented from working in leisure time, increased space game and referred to a psychologist or psychiatrist.