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The Potential Drug Interactions In Pediatrics Intensive Care Unit :A case study Of Imam Hussein Hospital in Isfahan.
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Maryam Azimi   , Akram Sanagoo , Leila Jouybari |
| , a_sanagu@yahoo.com |
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Abstract: (13691 Views) |
Introduction : Regarding to pharmacologic treatment complexity, patients in intensive care unit encounter with more drug interaction. The present study was conducted to investigate the drug interactions in pediatric intensive care unit in Emam Hossein pediatric Hospital, Isfahan, Iran.
Methods: In this cross- section study, the first 24 hour prescriptions of 100 patients admitted in pediatric intensive care unit of Emam Hossein Hospital, Isfahan, Iran during a five months period were investigated. The number and type of drug interaction and other factors such as number of prescribed drugs, medical diagnosis, age, gender and length of IC. In order to determine the number and type of hospitalization in this ward were assessed. The “Interaction Facts” reference textbook was used for drug interaction determining. The data were analysis using statistic tests such as Pierson correlation test and student t-test and one way Anova.
Results: Findings of study showed that overlay, 800 drugs in 99 different cases were prescribed with average of 8±2.79 for each patient. Overall, 194 drug interactions were found among critical care unit patients in the first 24 hour of prescription. Delayed, moderate, and possible interactions were addressed the most interactions. The results showed a significant correlation between the number of drug interactions and prescribed medications number, gender and duration of hospitalizations period(P<0.05).
Conclusions: Knowledge of drug interaction, replacing of interacting drug with other drugs as much as possible, noticing of highly interacting drugs, deminishing number of prescribed drugs can reduce PDI number and its consequences. |
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| Keywords: Drug interaction, patient, Pediatric Intensive Cares Unit |
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Full-Text [PDF 672 kb]
(3673 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/02/1 | Accepted: 2015/05/25 | Published: 2015/06/11
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